Read e-book online Aging is a group-selected adaptation: theory, evidence, and PDF

By Joshua Mitteldorf

ISBN-10: 1315354039

ISBN-13: 9781315354033

ISBN-10: 1498715281

ISBN-13: 9781498715287

ISBN-10: 1498715303

ISBN-13: 9781498715300

Because the Nineties, laboratory characterization of getting older has been diverging from predictions of evolutionary thought, specially within the zone of genetics. at the same time, a technological know-how of multilevel choice has chanced on its position within the evolutionary literature. the writer means that facts warrants attention of a brand new paradigm for evolution of getting older, and proposes the demographic idea of senescence, wherein getting older has Read more...

summary: because the Nineties, laboratory characterization of getting older has been diverging from predictions of evolutionary concept, in particular within the sector of genetics. simultaneously, a technology of multilevel choice has came across its position within the evolutionary literature. the writer means that proof warrants attention of a brand new paradigm for evolution of getting older, and proposes the demographic conception of senescence, wherein getting older has been affirmatively chosen since it degrees the loss of life fee through the years, supporting to stabilize inhabitants dynamics and forestall extinctions

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Additional info for Aging is a group-selected adaptation: theory, evidence, and medical implications

Sample text

Chemical hormetic phenomena are reviewed by Calabrese [79] and by Forbes [87]. Radiation hormesis has been reviewed by Luckey [88-90] and by Neafsey [91], updated by Jolly [92]. Hormesis 17 What all hormetic phenomena have in common is that the animal is treated in some way that we have good reason to believe ought to be harmful. Not surprisingly, the animal’s strength and resistance rise in response. But what is completely unexpected: the body overcompensates, so that over the long haul, the animal does better and lives longer.

Elegans. Science, 2002. 298(5594): p. 830-4. 57. Hsin, H. and C. Kenyon, Signals from the reproductive system regulate the life span of C. elegans. Nature, 1999. 399(6734): p. 362-366. 58. , The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake. J. , 1986. 116(4): p. 641-54. 59. , Dietary modulation of reproductive function, In: Modulation of Aging Processes by Dietary Restriction, B. Yu, Editor. 1994, CRC Press: Cleveland, OH. p. 221-246.

Hormesis 5 titled Discorsi della vita sobria (Discourses on the Temperate Life) about his personal experiments with caloric restriction, supplemented by half a litre of wine daily. Cornaro lived to 102. ” (Franklin grew portly and died of pleurisy, an inflammatory disease, at age 84). In the depression of the 1930s, the issue of widespread malnutrition was discussed in America. How would it affect people’s health and longevity if they did not have enough to eat? Would children’s growth be stunted permanently?

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Aging is a group-selected adaptation: theory, evidence, and medical implications by Joshua Mitteldorf


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