By Vincent J. Cristofalo PhD
This quantity offers a transparent, concise evaluation of the present country of information in regards to the biology of getting older √± serving as either a useful graduate-level textual content and a key reference for working towards pros. Over a dozen individual participants probe the newest advancements in our wisdom of why humans age and the way the method works. those authoritative chapters will not be simply written for biologists √± yet for gerontologists regularly. Marks the 10th anniversary of the yearly assessment of Gerontology and Geriatrics.
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Over the last 15 years the examine on homocysteine and the supplements occupied with its metabolism has develop into very dynamic. approximately 1,500 guides at the topic are actually released every year. The study has lengthy in general concerned about the organization among homocysteine and heart problems, but in addition being pregnant issues/ fetal malformations.
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Extra info for Annual Review of Gerontology and Geriatrics, Volume 10, 1990: Biology of Aging
214). New York: Van Nostrand Reinhold. Burnet, M. (1974). Intrinsic mutagenesis: A genetic approach for aging. New York: Wiley. Carrel, A. (1912). On the permanent life of tissues outside the organism. Journal of Experimental Medicine, 15, 516. Carrel, A. (1914). Present condition of a strain of connective tissue twenty-eight months old. Journal of Experimental Medicine, 20, 1. , & Burrows, M. T. (1911). On the physiochemical regulation of the growth of tissues. Journal of Experimental Medicine, 13, 562.
Increased error frequency of DNA polymerases from senescent human fibroblasts. Journal of Molecular Biology, 146, 55. Oliver, C. , et al. (1985). Age-related alterations of enzymes may involve mixedfunction oxidation reactions. In R. C. Adelman, & E. E. ), Modification of Proteins During Aging (p. 39). New York: Alan Liss. BIOLOGICAL MECHANISM OF AGING 21 Orgel, L. E. (1963). The maintenance of the accuracy of protein synthesis and its relevance to aging. Proceedings of the National Academy of Sciences of the USA, 49, 517.
Culture characteristics of human fibroblasts propagated serially. American Journal of Hygiene, 45, 20. Szilard, L. (1959). On the nature of the aging process. Proceedings of the National Academy of Sciences of the USA, 45, 30. Tice, R. , & Setlow, R. B. (1985). DNA repair and replication in aging organisms and cells. In C. E. Fench, & E. L. ), Handbook of the biology of aging (p. 173). New York: Van Nostrand-Rheinhold. Tolmasoff, J. , et al. (1980). Superoxide dismutase: Correlation with life span and specific metabolic rate in primate species.
Annual Review of Gerontology and Geriatrics, Volume 10, 1990: Biology of Aging by Vincent J. Cristofalo PhD